ГОСТ ISO 10993-16-2016
studies. II. Generic physiologically based pharmacokinetic models of drug
disposition, J. Pharm. Sci., 91, pp. 1358-1370, 2002
[51] RENWICK, A.G. and LAZARUS, N.R., Human variability and noncancer risk
assessment — An analysis of the default uncertainty factor,. Regul. Toxicol.
Pharmacol., 27, pp. 3-20,1998
[52] ROFFEY, S.J., OBACH, R.S., GEDGE, J.l. and SMITH, D.A, What is the
objective of the mass balance study? A retrospective analysis of data in animal
and human excretion studies employing radiolabelied drugs, Drug Metab. Revs.,
39, pp. 17-44,2007
[53] ROSSO, F., MARINO, G., GIORDANO, A., BARBARISI, M., PARMEGGIANI, D.
and BARBARISI, A, Smart materials as scaffolds for tissue engineering, J. Cell
Physiol., 203, pp. 465-470,2005
[54] SCARFE,G.B., et al., 19F-NMRand directly coupled HPLC-NMR-MS
investigations into the metabolism of 2-bromo-4-trifluoromethylaniline in rat: a
urinary excretion balance study without the use of radiolabelling,Xenobiotica,28,
pp. 373-388,1998
[55] SHEINER, L.B. and STEIMER, J-L, Pharmacokinetic/pharmacodynamic modelling
in drug development. Ann. Rev. Pharmacol. Toxicol., 40, pp. 67-95,2000
[56] SKORDI,E.,WILSON,I.D.,LINDON,J.C.andNICKOLSON,J.K.,
Characterization and quantification of metabolites of racemic ketoprofen excreted
in urine following oral administration to man by 1H-NMR spectroscopy, directly
coupled HPLC-MS and HPLC-NMR, and circular dichroism, Xenobiotica, 34, pp.
1075-1089,2004
[57] SLATTER, J.G., et al., Pharmacokinetics, toxicokinetics, distribution, metabolism
and excretion of linezolid in mouse, rat and dog,. Xenobiotica, 32, pp. 907-924,
2002
[58] SMITH, D.A., WALKER, D.K. and VAN de WATERBEEMD, H., Pharmacokinetics
and metabolism in drug design. Methods and principles in medicinal chemistry,
31, Wiley-VCH, Weinheim, 2006
[59] SMITH, D.A., HUMPHREY, M.J., and CHARUEL, C., Design of toxicokinetic
studies, Xenobiotica, 20, pp. 1187-1199,1990
[60] SMITH,D.A., Pharmacokineticsandpharmacodynamicsintoxicology,
Xenobiotica,27, pp. 513-525, 1997
[61] SUN, H.F., MEI, L„ CUNXIAN, S., CUI, X., and WANG, P., The in vivo
19